Kicking off Week 6 of the 2024 NFL season with a clash between division rivals, the San Francisco 49ers (2-3) will take on the Seattle Seahawks (3-2) in Thursday’s primetime affair.
Bet on 49ers vs. Seahawks
SF -3.5
SEA +3.5
As both sides look to put an end to their current losing streaks, this week’s matchup will also decide who will take control over the NFC West. With plenty of drama involved in the Week 6 opener, why not crank up the heat surrounding the 49ers vs. Seahawks by placing a bet on the action?
At CSB, we’ve compiled the best picks & predictions on the 49ers vs. Seahawks so you can boost your bankroll using the latest Thursday Night Football odds. Along with our expert analysis, our Thursday Night Football betting preview also features betting trends for both players and teams, as well as the latest updates on the injury report and weather forecast.
Get some skin in on the game for Thursday Night Football and tail our picks for the 49ers vs. Seahawks this evening.
| 49ers Moneyline Odds | -182 |
| Seahawks Moneyline Odds | +150 |
| Spread odds | 49ers -3.5 (-105), Seahawks +3.5 (-115) |
| Over/Under | 48.5 points (over -115, under -105) |
| Time/Date | Oct. 10, 8:15 p.m. ET |
| TV | Broadcast: TSN/DAZN |
All odds courtesy of BetVictor Canada
Betting San Francisco 49ers (2-3 SU, 2-3 ATS, 3-2 o/u)
Off to a shaky start to their 2024 season, the panic button is out of its case and on the table for 49ers faithful. After blowing a fourth-quarter lead to the Arizona Cardinals in Week 5, the 49ers have struggled to maintain consistent play so far this season.
With star running back Christian McCaffrey still out of action as well as the lacklustre play of wide receiver Deebo Samuel to start their season, the Niners offence has looked stagnant at times. Their disappointing play is evident in their betting trends so far this season as they have a losing record against the spread.
In desperate need of a win in Week 6, this divisional meeting with the Seahawks could be a pivotal moment in the early goings of the 49ers’ season.
Betting Seattle Seahawks (3-2 SU, 1-3-1 ATS, 4-1 o/u)
After coming out the gates hot with a 3-0 start to the season, the Seahawks have cooled off after dropping back-to-back games to the Detroit Lions and New York Giants, respectively. While expectations were high to begin the season, the Seahawks are now feeling the pressure heading into primetime.
With a putrid record against the spread, the Seahawks have not been a reliable betting team. While they’ve managed to go 2-2 as a favourite straight-up, their lone game as an underdog has resulted in a loss. Although the Seahawks have been inconsistent in terms of wins and losses, they have consistently been a part of high-scoring shootouts, currently tied for the best over rate in the NFL this season (80%).
Hoping to retain their top spot in the NFC West, this Thursday Night Football clash may indicate the ceiling of this Seahawks squad in 2024.
Betting Mismatch
On track to put up a career high in passing yards this season, look for Seahawks quarterback, Geno Smith to torch the 49ers this evening as he racks up Over 252.5 passing yards.
Averaging 293.3 passing yards per game through the first five weeks of the 2024 NFL season, Smith has exploded in production to begin his current campaign. Utilizing his three-headed monster of DK Metcalf, Tyler Lockett, and Jaxson Smith-Njigba to perfection, the veteran quarterback has had no trouble piling up passing yards in his 11th NFL season.
Facing a 49ers defence that is set to be missing key members of its secondary in Thursday’s clash, look for Smith to take full advantage as he attacks them through the air repeatedly en route to a stellar statistical showing. Bet the Over on his passing yards as he easily eclipses 252.5 yards on Thursday Night Football.
Geno Smith Over 252.5 Passing Yards
-118
Key Injuries
Coming off of a short week, injuries are beginning to pile up across the NFL and will be evident in this Thursday Night Football matchup.
For the 49ers, their secondary has taken a hit as starting safety, Talanoa Hufanga has been ruled out of action due to torn wrist ligaments suffered in their Week 5 loss to the Cardinals. Additionally, top cornerback Charvarius Ward is listed as questionable alongside All-Pros linebacker Fred Warner, and tight end George Kittle.
Licking their own wounds heading into their primetime tilt with the 49ers, the Seahawks have also been hit with some troubling injury concerns. Linebacker Uchenna Nwosu was moved to the team’s IR after suffering a thigh injury in Week 5. Notable members of the ‘Hawks secondary in Julian Love and Tariq Woolen are listed as questionable to compete against the Niners.
Weather
As temperatures begin to drop in the northwest of the United States, the weather in Seattle is set to be fair on Thursday Night Football. With temperatures in the range of 14 C, with low winds and no forecast of rain, the weather shouldn’t play a factor in the 49ers vs. Seahawks.
NFL Betting Trends
- The 49ers have won five straight head-to-head meetings with the Seahawks, including a postseason clash in the 2022 Wild Card Round.
- Since 2022, the 49ers are 7-4 SU coming off of a loss.
- The Seahawks are 5-8 ATS in divisional matchups dating back to 2022.
- The Seahawks are 4-2 ATS as home underdogs since 2022.
NFL Player Prop Trends
- 49ers quarterback Brock Purdy has thrown for Over 1.5 touchdown passes in two of his three career starts against the Seahawks.
- 49ers running back Jordan Mason’s rushing yard total currently sits at 81 yards. He has hit the Over on this mark in four of his five games played this season.
- In his last three appearances against the 49ers, Seahawks running back Kenneth Walker III has rushed for an average of 26 yards per game. His current rushing yards total is set at 57.
- Seahawks wide receiver DK Metcalf has failed to record more than 55 receiving yards against the 49ers in four consecutive games played. His receiving yard total is set at 63.5 yards.
49ers vs. Seahawks Predictions
- Set to put forth a competitive effort against their top competition within their division, back the Seahawks to cover the spread against the 49ers in their upcoming clash. The 49ers have struggled to keep explosive teams from generating big plays down the stretch of games, and with members of their secondary continuing to drop like flies, look for the Seahawks to remain in striking distance all game long as they utilize their top-tier passing attack to put pressure on the visiting favourites, covering the 3.5-point spread en route to a potential underdog upset.
- There’s sure to be no shortage of points scored on Thursday Night Football so make sure to hammer the Over on the 49ers vs. Seahawks. With both sides coming off of high-scoring affairs, coupled with their weakened defensive corps, points are sure to come early and often in this primetime battle between bitter rivals.
