Set to usher in the latest crop of NFL stars live from Green Bay, Wisconsin, the 2025 NFL Draft features several highly-touted prospects that are projected to take the league by storm. With each team set to be on the clock, why not get some skin in on this year’s draft like your in the War Room yourself by placing a bet on the latest NFL Draft odds.
At CSB, we’ve featured some of our expert picks on this year’s event with our 2025 NFL Draft betting preview. Below you can find several moneymaking bets that are sure to have your bankroll booming by the time the first round comes to a close.
Don’t wait, check out our list of the top NFL betting sites in Canada, sign up, and place your first bet on the 2025 NFL Draft odds today.
Our 2025 NFL Draft Betting Picks
Sites like bet365, Sports Interaction, and BET99 offer the best NFL draft odds coming up on April 24th, so be sure to sign up and get your bets ready for draft day. Scroll down for our top betting picks to cash in on this weekend.
Abdul Carter: Drafted Second Overall (+475)
In what’s set to be a nail-biting start to the 2025 NFL Draft, look for Penn State edge-rusher, Abdul Carter to have his name called as the second pick in this year’s draft class.
With Miami quarterback, Cam Ward the consensus first overall pick, this leaves the second overall selection between Carter and Heisman winner, Travis Hunter. While Hunter currently has strong odds indicating that he will be taken second overall, we wouldn’t bank on that becoming a fact.
As the Cleveland Browns are currently positioned to draft with the second overall pick, we can see them continue to bolster their front-seven, rather than opting-into the dual-threat ability of Hunter. While Hunter is truly a one of a kind player, there’s still plenty of speculation as to his ability to become elite at either position at the NFL level.
From a team needs perspective, Carter may be the better fit for the Browns as well. In the rough-and-tumble AFC North, trench warfare is often how the division is won. After inking Myles Garrett to a lucrative extension this offseason, pairing Carter with him could create one of the leagues most fearsome pass-rushing duos, while positioning themselves to maintain an elite defensive line for years to come.
There was a brief time where Carter was looked at as a potential number-one pick, making his case to be selected second overall a legitimate one. At +475 NFL draft odds, this is a great way to kickoff your NFL Draft bets with a bang.
Abdul Carter to Be Drafted Second Overall
Mason Graham: Drafted in the Top 5 (+120)
Primed to become the first interior defensive lineman selected in the 2025 NFL Draft, Michigan’s Mason Graham is a name to watch within the Top 5. With the consensus Top 3 of Ward, Carter, and Hunter seemingly a lock, this leaves just two spots open for Graham to have his name called, something we see having a great chance of happening, with plus-money attached to it.
The likely spot for Graham would be as the fifth overall draft choice to the Jacksonville Jaguars, as tackle Will Campbell from LSU is a popular pick to head to the New England Patriots at four. The Jags were putrid in stopping the run in 2024, allowing 132.6 yards against per game, ninth-worst across the entire NFL.
Needing a major boost to their porous defense, look for Graham to be the answer to their current issues, filling a massive hole in their roster, as well as adding a healthy dose of winnings into your account balance.
Mason Graham Drafted in the Top 5
Matthew Golden: First Wide Receiver Drafted (+150)
In a somewhat down year for wide receivers in entering into the NFL Draft, look for Texas wideout Matthew Golden to be the first wide receiver drafted this year.
After a successful junior year as a member of the Longhorns, Golden racked up 987 yards and nine touchdowns in his final year of his collegiate career. Further bolstering his draft stock during the NFL combine, registering the fastest 40-yard dash time of any wide receiver, second-fastest overall, Golden has the makings of the next great NFL wideout.
The only competition Golden has in the first round of the NFL Draft comes from Arizona Wildcat, Tetairoa McMillan, who had back-to-back sensational seasons within the PAC-12.
In the eyes of most analysts, this decision could boil down to a coin flip, but with the Dallas Cowboys likely to be the team that takes a receiver off the board first in this year’s draft, look for them to select from within the Lone Star State, taking Golden over McMillan and cashing this juicy NFL Draft prop bet.
Matthew Golden to be the First Wide Receiver Drafted
Mykel Williams: Over 15.5 Draft Position (+320)
One of the top defensive prospects in the 2025 NFL Draft, look for Georgia EDGE, Mykel Williams to fall in this year’s draft as he is selected after the 15th overall pick.
In a loaded draft class when it comes to defensive lineman, Williams is set to be the odd man out. Competing with the likes of Abdul Carter, Mike Green, Shemar Stewart, and Donovan Ezeiruaku, Williams likelihood of becoming a high draft pick is slim to none. While he will still be a first round pick the names featured ahead of him have proven they possess far greater upside and potential down the road of their careers.
After breaking out in his freshman season in which his Georgia Bulldogs captured the National Championship, he never truly improved from that season on. With his stats staying about the same for the entirety of his college career, look for NFL franchises to look elsewhere when selecting the pass-rusher for the future.
We project Williams to fall into the final few picks of the first round, with the Detroit Lions at #28 looking like a realistic scenario for the big man to be drafted at, well below the 15th spot oddsmakers see him going at.
Mykel Williams Under 15.5 Draft Position
Under 2.5 Wide Receivers Drafted in the First Round (+200)
As mentioned above when discussing who will be the first wide receiver off the board in the 2025 NFL Draft, this bet goes hand-in-hand with the weak talent pool available at the position. With Travis Hunter counting as a cornerback in the eyes of oddsmakers, Matthew Golden and Tetairoa McMillan are the only wideouts that will be drafted in the first round, meaning the Under 2.5 mark is a certified moneymaker for this year’s draft.
While some mock drafts may have players such as Luther Burden III, Emeka Egbuka, and Elic Ayomanor included in their first round projections, this is a very unlikely scenario. With most teams across the league possessing an established wide reciever corps., coupled with the superior depth of talent at other positions in the 2025 NFL Draft, it’s likely to see the second and third rounds be where we see receivers flying off the board at a high-rate.
Fade the amount of wide receivers drafted in the first round of the 2025 NFL Draft and cash-in on this profitable prop bet market in this year’s selection process.