Best March Madness Long Shot Picks to Win the 2025 NCAA Tournament

It’s officially one of the best times of the year as the page has flipped to March on the sports calendar, and with it, comes the 2025 NCAA Men’s Basketball Tournament.

With no shortage of highlight reel moments ahead of us that will live on forever in the hearts of college hoops fans across the globe, you don’t want to miss out on a second of the action.

Easily the biggest draw of March Madness comes from the unpredictability of every matchup with jaw-dropping upsets occurring routinely throughout the tournament. That’s why at CSB, we’ve compiled all the best March Madness long shot picks so you can boost your bankroll betting on this year’s event.

Check out our featured moneymaking futures picks & predictions below, see which teams we foresee putting together a Cinderella run, and watch your bankroll boom while everyone else’s brackets bust.

Maryland Terrapins (+5000)

Kicking off our March Madness long shot picks, we’ve got the four-seed from the West Region of the March Madness bracket, it’s the Maryland Terrapins.

Led by freshman phenom and potential top-10 pick in the 2025 NBA Draft, Derik Queen, Maryland has all the fixings to contend for a National Championship this season. Holding notable victories over top teams such as the Wisconsin Badgers and Illinois Fighting Illini this year, the Terrapins hope to finally break through the first weekend of March Madness since 2016.

An athletic squad that loves to push the pace offensively, Maryland is a terrific transition team. This strength has gone hand-in-hand with their standout defence, generating turnovers often and making their opposition pay on the other end.

At +5000, the Terrapins are a great long shot pick to back heading into the 2025 NCAA Tournament as they will look to outwork their opponents all the way toward the school’s first National Title since 2002.

Maryland to Win 2025 NCAA Tournament

+5000

Gonzaga Bulldogs (+5000)

A mainstay in the NCAA Tournament, the Gonzaga Bulldogs are always a great bet to go on a deep run through the March Madness bracket. Having made 10 consecutive Sweet Sixteens coming into this year’s event, it’s safe to say that the Bulldogs are more than ready for the big stage.

A well-oiled machine offensively, Gonzaga sports one of the best offences in the Nation. Scoring a sensational 86.6 points per game, the Bulldogs simply can’t be stopped once they get the ball in their half court offence.

Led by the NCAA leader in assists per game, Canadian, Ryan Nembhard, Gonzaga is primed for yet another sensational showing at the NCAA Tournament. At +5000 odds, this squad is far better than the typical eight-seed and are sure to show it once the action tips-off.

Gonzaga to Win 2025 NCAA Tournament

+5000

Texas A&M Aggies (+6600)

Coming out of the South Region with a legitimate chance to reach the Elite Eight for the first time in its school’s history, the Texas A&M Aggies have all the tools needed to go dancing this March.

Starting off the tournament with a favourable matchup against the Yale Bulldogs, the Aggies are set for a potentially advantageous path through their side of the bracket. Set for a potential matchup with the top-seeded Auburn Tigers in the Sweet Sixteen, the Aggies have legitimate upset potential as they’ve already defeated the Tigers once this season.

Additionally, the Aggies, while not the strongest offensive team, are always on the prowl for loose balls, and crash the offensive glass at the best rate in the NCAA. With their tenacity for controlling the boards and ability to outwork opponents through their physical brand of basketball, the Aggies are sure to cause frustration for every opponent faced.

At +6600, you can’t ask for better value from a top-four seeded team in the NCAA Tournament. Back Texas A&M and make a splash on your March Madness bets this year.

Texas A&M to Win 2025 NCAA Tournament

+6600

VCU Rams (+25000)

Capping off our 2025 March Madness long shot picks with our prediction to be this year’s Cinderella, the VCU Rams may be set to make history this year.

With experience of making a deep run in the March Madness bracket from the 11-seed, evident from their Final Four appearance in 2011, the Rams should be looked at as the top value bet in any March Madness futures market.

While the lowest-seeded squad to ever win it all was the 1985 Villanova Wildcats as the eight-seed, don’t let this deter you from getting some juice out of this long shot pick this March.

VCU has performed well against some of the top teams in the Nation with wins over the Kansas Jayhawks, Arizona Wildcats, as well as two victories against the Iowa State Cyclones. With a savvy squad full of seniors, great depth, and impressive defensive ability, the Rams are a tough matchup for any opponent.

Possessing terrific size coupled with a high-volume three-point shooting offence, the Rams are sure to catch the college basketball world by storm with their eye-catching style of play.

At a whopping +25000 odds to win the 2025 NCAA Tournament, that means just a $10 wager would payout $2,500 in profit. At that price, why not sprinkle some cash on this hungry underdog to take home the National Title as you make history alongside the Rams with this long shot bet.

VCU to Win 2025 NCAA Tournament

+25000