It’s officially do-or-die time in the NFC West as the division title is still up for grabs. In a game with massive playoff implications, expect to see an intense atmosphere on Thursday Night Football as the Los Angeles Rams take on the San Francisco 49ers.
Bet on Rams vs. 49ers
LAR +2.5
SF -2.5
There’s no better way to kick off NFL Week 15 than with a rivalry game and this upcoming clash is sure to produce fireworks. Both the Rams and 49ers are coming off big wins and will be looking to carry that momentum over into this primetime affair.
The only way this pivotal matchup could get any more exciting is by getting in on the action yourself by placing a bet on the Rams vs. 49ers. Below we’ve provided an in-depth betting preview for the latest Thursday Night Football odds, as well as our expert picks and predictions that are sure to help boost your bankroll.
Don’t wait, place your next winning wager on the NFL today with our Rams vs. 49ers betting preview.
| Rams Moneyline Odds | +115 |
| 49ers Moneyline Odds | -137 |
| Spread odds | 49ers -2.5 (-115), Rams +2.5 (-111) |
| Over/Under | 49.5 points (over -105, under -115) |
| Time/Date | Dec. 12, 8:15 p.m. ET |
| TV | Broadcast: TSN/DAZN |
Betting the Los Angeles Rams (7-6 SU, 6-7 ATS, 7-6 o/u)
Hot off the heels of their biggest win of the 2024 NFL season, the Rams stunned the football world with a victory over legitimate Super Bowl contenders in the Buffalo Bills. With elite play calling from head coach Sean McVay, the Rams have once again exceeded expectations and are jockeying for a potential division championship.
While their high-scoring slugfest with the Bills proved that at full strength the Rams are a tough team to face, this hasn’t been the case all season long.
With a mediocre record against the spread, the Rams have not been a reliable betting option in 2024. Along with a losing record against the spread, the Rams have been hot and cold when it comes to producing points within their games.
A somewhat difficult team to predict week by week, the Rams haven’t shown any clear betting trends in regards to the main game lines in 2024.
Betting the San Francisco 49ers (6-7 SU, 5-8 ATS, 7-6 o/u)
Experiencing no shortage of adversity this season, the 49ers are still alive in the NFC playoff hunt thanks to the rough shape of the NFC West. With a losing record after 14 weeks of play, the 49ers are still in play to secure a home playoff game if they’re able to win out down the stretch of the year.
While they continue to battle through injury woes up and down their lineup, the Niners still possess some star power that can help elevate them to a win.
Betting-wise, the 49ers have been even worse than their season record. With a dismal 5-8 record against the spread, the Niners have only managed to cover in 38.4% of their games played this season. Additionally, their scoring has struggled to remain consistent with their over/under trends essentially being a coin flip.
Betting Mismatch
Set to shine under the bright lights of Thursday Night Football, back 49ers star tight end George Kittle to record a touchdown against the Rams.
Having had success reaching the end zone in the past against the Rams, Kittle has recorded a touchdown in 50% of his games played against the Rams in his career, having put six on the board in four of his last seven head-to-head meetings.
Having scored in three of his last five outings, look for Kittle to utilize his nose for the end zone as the charismatic tight end shreds through the weak secondary of the Rams, putting his team on the scoreboard with his ninth touchdown grab of the season.
George Kittle Anytime Touchdown Scorer
+130
Key Injuries
injuries have become a common theme for both teams competing on Thursday Night Football and continue to be a prevalent factor heading into Week 15.
For the Rams, they’re healthier than they’ve been all season long, but still have a few injury tags placed on top contributors for their squad. Notable injuries include WR Demarcus Robinson, WR Jordan Whittington, and CB Cobie Durant all listed as questionable, while TE Tyler Higbee has already been ruled out of competing.
The 49ers are in worse shape than the Rams in terms of injury luck currently, with a plethora of top players sitting with injury designations. RB Isaac Guerrendo, OT Trent Williams, and DE Nick Bosa are all questionable to compete against the Rams. Whether or not they suit up could be the deciding factor in who wins this primetime clash.
NFL Betting Trends
- The Rams are 0-2 ATS as away underdogs in 2024.
- No strangers to high-scoring games in recent weeks, the Rams have been a part of matchups resulting in over 49.5 points scored in three of their last four games played.
- The 49ers are 1-3 ATS in divisional games this season.
- Having lacked consistency this season, the Niners are 0-5 ATS coming off of a win this season.
- In their previous matchup this season, the Rams defeated the 49ers, 27-24.
NFL Player Prop Trends
- Rams wide receiver Cooper Kupp has scored a touchdown in three of his last four games played. He is priced at +110 to hit pay dirt against the 49ers.
- Passing at a heavy clip, Rams quarterback Matthew Stafford has averaged 273 passing yards over his last seven games. With his line set at 242.5 yards, Stafford is a prime candidate to reach the over in this category.
- Connecting with his receivers routinely over his last five games played, 49ers quarterback Brock Purdy has exceeded 244.5 passing yards in three of his last five starts.
- Having recorded five or more receptions in four of his last five games played, 49ers Jauan Jennings is a great look to reach the over on his total receptions.
Rams vs. 49ers Predictions
- While the Rams may be the hot hand coming into Thursday Night Football, look for them to become frozen in their tracks as they’re bested by the 49ers this evening. As the 49ers are seemingly finding their groove down the stretch of the season, they match up incredibly well against this iteration of the Rams. Look for the 49ers to utilize their passing attack to keep the Rams on their heels, while their superior defence begins to string together stops. Back the 49ers to cover the 2.5-point spread and score yourself a big win as the 49ers keep their postseason hopes alive.
- In a matchup where both sides are set to swing for the fences, look for the score to quickly rise above 49.5 points. In their last head-to-head meeting, 51 total points were scored, a great indication of what’s to come this evening. As both sides have been a part of multiple high-scoring games in recent weeks, look for this trend to continue on Thursday Night Football as the over hits down he stretch of the ball game.
