Monday Night Football Odds, Betting Preview: Saints vs. Chiefs Predictions

Kansas City Chiefs tight end Travis Kelce (87), right, grins next to Kansas City Chiefs quarterback Patrick Mahomes (15) and Kansas City Chiefs guard Trey Smith (65) before they run onto the field to face the Chargers at the So-Fi Stadium on September 29, 2024 in Inglewood, California.

Capping off Week 5 of the NFL season with a bang, we’ve got a sensational matchup in store for us on Monday Night Football as the New Orleans Saints (2-2) take on the Kansas City Chiefs (4-0).

Bet on Saints vs. Chiefs

NO +5.5
KC -5.5

Facing off for the first time since 2020, the Chiefs will look to remain unbeaten against a live underdog in the explosive Saints. With both teams sporting no shortage of star power in Monday’s clash, there’s never been a better time to get some skin in on the game with the latest Monday Night Football odds.

Below, we’ve provided the best odds, picks, and trends on the Saints vs. Chiefs so you can stuff your bet slip with winning wagers for this primetime matchup. Along with our top moneymaking bets, we’ve provided expert analysis on the game from an analytical standpoint, as well as information on the latest line movement and weather updates around the game.

As kickoff is fast-approaching let’s dive into the odds, picks, and betting trends for Monday’s game between the Saints and Chiefs courtesy of bet365:

Saints vs. Chiefs odds

Saints Moneyline Odds+210
Chiefs Moneyline Odds-260
Spread oddsChiefs -5.5 (-110), Saints +5.5 (-110)
Over/UnderOver 43 points (-110), Under 43 points (-110)
Time/DateOct. 7, 8:15 p.m. ET
TVBroadcast: TSN/DAZN

About the Saints (2-2 SU, 3-1 ATS, 3-1 o/u)

After coming out the gates red hot to start their 2024-25 season, the Saints have cooled off a touch in recent weeks. Taking back-to-back losses against the Philadelphia Eagles and Atlanta Falcons, the Saints have still been a reliable betting option in 2024.

With a strong 3-1 record against the spread, the Saints have exceeded expectations set by oddsmakers routinely so far this season. Additionally, the Saints have been in a number of high-scoring shootouts, resulting in 75% of their games having hit the Over in their current campaign.

About the Chiefs (4-0 SU, 3-1 ATS, 2-2 o/u)

Still in command of the NFL as they remain undefeated through Week 4, the Chiefs certainly haven’t been their dominant selves to begin the season. With a plethora of injuries suffered to top players to begin their campaign, the Chiefs’ future outlook could be scary.

While the future of their season is uncertain, so far this year they’ve been a great betting option. Having won four straight games outright, all four coming as favourites, the Chiefs have been a moneymaker this season. Additionally, they’ve been strong against the spread, covering in three of their four games played thus far.

Line Movement

There hasn’t been a ton of line movement for the Saints vs. Chiefs. Opening the week, the spread was set at 5 points, and the point total was 42.5. Since then the spread and point total has shifted by a half-point each. In the offseason, this game was originally projected at an eight-point spread in favour of the Chiefs, with a point total line of 44.5. This line has largely shifted as the Saints have been better than expected, coupled with the Chiefs’ injury woes.

Key Injuries

In a fluke injury inflected by Patrick Mahomes after a turnover, the Chiefs lost yet another key member of their offence in wide receiver Rashee Rice. Joining fellow wideout Hollywood Brown and running back Isiah Pacheco on the Chiefs IR, the defending Super Bowl champions are having to look deep in their depth chart for production. Along with Rice, running back Clyde Edwards-Helaire is out of action for Monday Night Football.

For the Saints, there are several key contributors listed as out: LB Willie Gay Jr., TE Taysom Hill, C/G Cesar Ruiz, C/G Shane Lemieux, and DE Payton Turner. A major loss for the Saints offence comes from their gadget player Hill as he was diagnosed with fractured ribs earlier this week and is set to miss Monday Night Football.

Weather

Taking place at Arrowhead Stadium in Kansas City, Missouri, the weather conditions look to be fair heading into Monday Night Football. With temperatures of about 15 C and light winds, there’s no need to worry about weather playing a factor in the outcome of the ball game or your bets.

  • Both of the Saints’ losses this season have been by three or less points. The spread is currently 5.5 points.
  • Since the 2023 season, the Saints are 4-2 ATS as underdogs.
  • Patrick Mahomes is 7-3 SU on Monday Night Football.
  • Since the 2022 season, the Chiefs are 9-3-1 ATS in non-conference games.
  • Alvin Kamara has scored six touchdowns through the first four weeks of the season. He is currently listed at -110 as an anytime touchdown scorer.
  • In 11 Monday Night Football appearances, Derek Carr has passed for Over 211.5 passing yards eight times.
  • Averaging 10.5 yards per reception, Travis Kelce is primed for ample involvement in the Chiefs passing attack.
  • Having been used in the rushing attack in three of his first four career games, Chiefs wide receiver Xavier Worthy has racked up 39 rushing yards on five carries. With his line set at a measly 2.5 yards, he should easily exceed this if given a handoff attempt.

Alvin Kamara Anytime Touchdown Scorer

-110

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Saints vs. Chiefs Predictions

  • When it comes to winning the matchup outright, the smart money resides on the Chiefs. While Kansas City may take the win on Monday Night Football, it is likely going to be by the skin of their teeth. The Saints have proven themselves as tough competition for any team in the NFL this season, having pushed top contenders in the Eagles and Falcons to the limit in their only losses of the year. Hammer the Saints +5.5 as they remain in striking distance of the lead throughout the duration of Monday Night Football.
  • Both sides of this matchup have seen their fair share of high-scoring affairs, but look for the scoring output from each team to be minimal on Monday Night Football. With the Saints sporting a sensational defence that can easily keep the banged-up Chiefs offence in check, it’s sure to be a low-scoring night. Inversely, the Saints offence has proven to be untrustworthy for bettors in the past and should remain a fade option when taking on one of the top pass-rushes in the NFL. Bet the Under on the Saints vs. Chiefs and watch your account balance rise while the score stays low.